RESEARCH AND DEVELOPMENT
AT ALKEM ACTIVA
Ensuring Quality, Consistency, And Reliability

Our R&D department at Alkem Activa is at the forefront of Active Pharmaceutical Ingredient (API) development, driving advancements in pharmaceutical science and healthcare. Here's a closer look at our API development initiatives

Our Approach: Quality is Our Cornerstone
At Alkem Activa, we understand the critical role that APIs play in the pharmaceutical manufacturing process. These essential ingredients form the backbone of countless healthcare solutions, impacting patient well-being worldwide. Our approach is centered on quality assurance, ensuring that every API we produce meets the highest standards of safety and efficacy.

Every project undertaken by our R&D team is anchored in a commitment to reliability, ensuring consistency and excellence. In order to prevent the existence of nitrosamine impurities, our team of R&D professionals created processes and analytical methods that are already suitable to confirm future requirements of the EMA.

Cutting-Edge Facilities:
Our R&D team operates in state-of-the-art laboratories equipped with advanced research tools and technology. Our research is bolstered by high-throughput screening capabilities, enabling the rapid testing and evaluation of potential APIs. Our advanced analytical chemistry techniques ensure the accurate characterization and quality assessment of APIs.

We have sophisticated instruments like Bruker Nuclear Magnetic Resonance (NMR), triple quad Liquid Chromatography with tandem mass spectrometry (LCMSMS), Gas Chromatography-Tandem Mass Spectrometry (GCMSMS), X-ray crystallography (XRD), High-performance liquid chromatography (HPLC), Ion chromatograph, Differential scanning calorimetry (DSC) and Thermogravimetric analyzers (TGA)

Innovative Talent:
Our dedicated 70+ scientist scientists and researchers drive progress with groundbreaking experiments and projects.

OUR R&D CAPABILITIES

A state-of-the-art facility with advanced chemical synthesis labs, analytical development labs, kilo lab, high pressure lab and safety study lab.

A team of qualified, well trained and dedicated scientists specialize in developing innovative processes/technologies with global regulatory requirements

Our strong expertise in QbD (Quality by design) & DoE (Design of Experiments) enables us to increase process robustness and ease scale-up at plant

REACTION CAPABILITIES
  • Asymmetric Synthesis/Chiral Resolution
  • High Pressure Reactions (For example, Hydrogenation, Hydrogenolysis Ammonolysis etc)
  • Enzymatic Reactions
  • Coupling Reactions using Organometallic Catalyst
  • Oxidation
  • Reduction
  • Alkylation/Acylation
  • Bromination
  • Nitration
  • Condensation Reactions
  • Cryogenic Reactions (For Example, reaction using strong base like BuLi, LDA, NaH etc)
  • Esterification / Transesterifcation / Hydrolysis and many other reactions